Intracellular immunoglobulin distribution of bone marrow plasma cells as a diagnostic aid for primary amyloidosis.

نویسندگان

  • C Thielemans
  • W Aelbrecht
  • D Verbeelen
  • G Somers
  • M De Waele
  • B Van Camp
چکیده

In order to classify the underlying disorder in four patients with biopsy-proven amyloidosis without overt monoclonal gammopathy, the cytoplasmic immunoglobulin (Ig) distribution of bone marrow plasma cells was evaluated using direct immunofluorescence microscopy. This procedure revealed the presence of a monoclonal proliferation of light chain containing plasma cells, and thus led to the diagnosis of immunoglobulin-related amyloidosis.

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عنوان ژورنال:
  • Journal of clinical pathology

دوره 35 3  شماره 

صفحات  -

تاریخ انتشار 1982